CXCR1 and CXCR2 Inhibition by Ladarixin Improves Neutrophil-Dependent Airway Inflammation in Mice
RationaleIncreased IL-8 levels and neutrophil accumulation in the airways are common features found in patients affected by pulmonary Intermediate diseases such as Asthma, Idiopathic Pulmonary Fibrosis, Influenza-A infection and COPD.Chronic neutrophilic inflammation is usually corticosteroid insensitive and may be relevant in the progression of th